More than two decades after “How I Learned to Drive” won the Pulitzer Prize for drama, the play will make its debut on Broadway.

The play’s original stars, Mary-Louise Parker and David Morse, who created the roles for an Off Broadway production in 1997, will reunite for the Broadway production next year.

“How I Learned to Drive,” by Paula Vogel, is a widely staged memory play about a woman reckoning with years of sexual abuse by her uncle.

The play is being presented by a nonprofit, the Manhattan Theater Club, with support from the commercial producers Daryl Roth, Cody Lassen and the Dodgers, and in association with the Off Broadway nonprofit that originally presented the show, the Vineyard Theater. It is scheduled to begin previews March 27 and to open April 22 at the Samuel J. Friedman Theater.

For Ms. Parker, who won a Tony Award in 2001 for “Proof,” the project means double duty in more than one way: Not only will she be reprising a role she played 23 years earlier, but it is her second Broadway show this season. She is also starring in “The Sound Inside,” a play by Adam Rapp that is scheduled to open in October.

Mr. Morse was nominated for a Tony Award last year for “The Iceman Cometh.”

The Broadway production will be directed by Mark Brokaw, who also directed the original production, which started at the Vineyard and then transferred to a commercial run produced by Ms. Roth and Roy Gabay.

Michael Paulson is the theater reporter. He previously covered religion, and was part of the Boston Globe team whose coverage of clergy sexual abuse in the Catholic Church won the Pulitzer Prize for Public Service. @MichaelPaulson

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